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(0)Doris M Kupfer
Author
Publisher
Federal Aviation Administration, Office of Aerospace Medicine
Pub. Date
2010.
Language
English
Description
"Gene expression changes resulting from conditions such as disease, environmental stimuli, and drug use can be monitored in the blood. However, a less invasive method of sample collection is of interest because of the discomfort and specialized personnel necessary for blood sampling, especially if multiple samples are being collected. Buccal mucosa (cheek swabs) are easily collected and may be an alternative sample material for biomarker testing....
Publisher
Federal Aviation Administration, Office of Aerospace Medicine
Pub. Date
2008.
Language
English
Description
"An assay using the Federal Bureau of Investigation's human Combined DNA Identity System (CODIS) primers has been developed for polymerase chain reaction (PCR)-based human identity testing. Recent forensic literature has identified several human populations that carry a deletion mutation in the Y-chromosome copy of the amelogenin locus. This is the standard locus used for gender determination in CODIS. Additionally, the amelogenin male PCR products...
Series
DOT/FAA/AM volume 06/14
Publisher
Federal Aviation Administration, Office of Aerospace Medicine
Pub. Date
2006.
Language
English
Description
In this study, the Federal Bureau of Investigation's human Combined DNA Indentity System (CODIS) loci were used on a rapid, inexpensive microfluidics chip electrophoresis platform to confirm the identity of forensic samples from an aircraft accident site. Absolute allele identification was not achieved with this method, but it was found to be suitable for comparative analysis, as demonstrated by validation of the results and conclusions from cappllary...
Author
Publisher
Federal Aviation Administration, Office of Aerospace Medicine
Pub. Date
2009.
Language
English
Description
"An assay has been developed for polymerase chain reaction (PCR)-based human identity testing using the Federal Bureau of Investigation's human Combined DNA Identity System (CODIS) primers. Recent forensic literature has identified difficulties using these primers due to amplicon size and the degraded nature of DNA from forensic samples. Primers termed mini Short-Tandem Repeat (STR) primers targeted to the same loci as the CODIS primers but which...
Author
Publisher
Federal Aviation Administration, Office of Aerospace Medicine
Pub. Date
2009.
Language
English
Description
"Biological samples from the victims of aviation accidents are submitted to the Civil Aerospace Medical Institute (CAMI) for toxicological evaluation. Body components of aviation accident fatalities are often scattered, disintegrated, commingled, contaminated, and/or putrefied at accident scenes. These situations may impose difficulties in victim identification and tissue matching, thereby in the toxicological analysis of authentic samples and the...
